This is a must-see video. Conan O'Brien was asked to give the commencement address at Dartmouth and he gave, what could be the best graduation speech you've heard. Conan used a lot of humor in his speech which everyone always enjoys, but near the end of his speech he changed his tune.

Near the end of his speech Conan discussed his ouster at NBC and what followed when Jay Leno took over The Tonight Show. Conan talked about how your path may not be what it is ten years from now. He told graduates that disappointment will come, but how you handle defines you. Disappointment doesn't define you, how you handle it does. Great advice. Take a bit of time and check out the video below.